EPRUI Biotech Co. Ltd. supplies various magnetic beads including iron oxide nanoparticles, polymer magnetic beads and silica magnetic beads.

Our magnetic beads have two types: Sandwich type and Core Shell type.

1.Magnetic beads with sandwich type have a polymer core, and a layer of magnetic oxide: Fe2O3 or Fe3O4 nanoparticles in the middle between the polymer core and the outermost layer which is either inorganic or functionalized organic material, which completely covers the magnetic oxide layer to prevent it from potentially incompatible interaction with biomaterials.

magnetic beads with sandwich structure

2.Magnetic microspheres with core shell structure in which the core is Fe2O3 or Fe3O4 nanoparticles, and the shell is either inorganic or organic material. The surface of the particle is equipped with various functional groups such as amino, epoxy, carboxyl, and hydroxyl, etc. for different applications. This type of magnetic particles has large specific surface area and high magnetic content.

magnetic particles with core shell structure

EPRUI’s magnetic particles have narrow particle size distribution, higher magnetic content, and high specific surface area. EPRUI also have magnetic beads treated with different functional groups such as hydroxyl (-OH), carboxyl (-COOH), amine (-NH2) and epoxy, which can be applied for target and separation of bioactive substances.

magnetic-beads-description1

Magnetic particles are widely used in the area of diagnostic reagents, biological imaging, targeted drug carriers, DNA/RNA/Protein/ Polypeptide purification, effective separation of biomolecules, cells as well as a catalyst support. For example, magnetic beads pre-coated with antibodies against specific cell surface antigens can be used for cell separation. EPRUI Biotech is able to tailor magnetic particles with different particle size and functional groups for various uses.

EPRUI Biotech’s silica coated magnetic beads have a core-shell structure of magnetic oxide core and silica shell, which are designed for nucleic acid separation and purification. Due to their superparamagnetic properties, the nucleic acids can be directly isolated from complicated biological system by simple mixing of the silica beads and samples.

magnetic-beads-description2Our monodisperse magnetic beads with carboxyl groups can be attached with ligands by specific reagents such as EDC, which are designed to apply for protein purification, cell sorting and affinity chromatography.

magnetic-beads-description4

magnetic-beads-description5

Fig. 1. DNA separation of EPRUI magnetic silica beads and competitor’s (A: EPRUI MagSi; B: Competitor’s)

Brand Product Name Functional Groups Code No. Particle Size
MagOH Hydroxyl Magnetic Beads -OH 100020 200nm
100100 1um
100300 3um
100500 5um
101100 10um
MagSi Silica coated Magnetic Beads -SiOH 110020 200nm
110100 1um
110300 3um
110500 5um
111100 10um
MagNH2 Amino treated Magnetic Silica Beads -NH2 120020 200nm
120100 1um
120300 3um
120500 5um
121100 10um
Amino functionalized magnetic polystyrene beads -NH2 130020 200nm
130100 1um
130300 3um
130500 5um
131100 10um
MagCOOH Carboxyl treated

Magnetic Silica Beads

-COOH

140020 200nm
140100 1um
140300 3um
140500 5um
141100 10um
Carboxyl functionalized magnetic polystyrene beads -COOH 150020 200nm
150100 1um
150300 3um
150500 5um
151100 10um
Magepoxy Epoxy treated Magnetic Silica Beads Epoxy 160020 200nm
160100 1um
160300 3um
160500 5um
161100 10um
Epoxy treated Magnetic Polystyrene Beads Epoxy 170020 200nm
170100 1um
170300 3um
170500 5um
171100 10um